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Dbol Dianabol Cycle: How Strong Is Methandrostenolone?

How Testosterone Works in the Body





Production & Release


- In men: produced by Leydig cells in the testes (≈95 %) and a small amount by adrenal glands.

- In women: mainly from ovarian follicles and the adrenal cortex.

- Circulates mostly bound to sex‑binding globulin (SHBG) or albumin; only the free fraction is biologically active.





Target Cells & Receptors


- Enters cells via diffusion, binds to intracellular androgen receptors (AR).

- The hormone–receptor complex translocates to the nucleus and acts as a transcription factor, turning on genes that mediate growth, differentiation, or metabolic effects.





Physiological Actions


- Male reproductive system: promotes spermatogenesis, libido, secondary sexual characteristics (facial hair, deepening voice).

- Muscle & bone: increases protein synthesis and bone mineral density.

- Fat metabolism: influences lipolysis and adipocyte differentiation.

- Cognitive effects: evidence of mood regulation and neuroprotection.





Clinical Relevance


- Disorders such as hypogonadism, delayed puberty, or infertility may be treated with testosterone replacement.

- Understanding the hormone’s pathways aids in developing targeted therapies for androgenic disorders and minimizing side‑effects (e.g., cardiovascular risk).



In summary, the hormone described is testosterone, a steroid secreted by Leydig cells that exerts wide‑ranging biological effects through its receptor-mediated actions on diverse tissues.
Gender : Male